Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in complete remission. However, cancer cells have a remarkable capacity to evolve resistance ...

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them—throw them in the cellular trash. In a new study published in ...

Scientists report landmark "evolutionary double-bind" strategy to overcome treatment resistance in prostate cancer.

Scientists have uncovered an unexpected reason why some cancers return after initially responding to treatment.

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows.

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a ...

Scientists at UCLA have developed an "off-the-shelf" cell-based immunotherapy that was able to track down and kill pancreatic cancer cells even after they had spread to other organs. In a mouse study, ...

Scientists have uncovered a surprising way tumors turn the immune system to their advantage. Researchers at the University of Geneva found that neutrophils—normally frontline defenders against ...

Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based ...

Cancer cells can brainwash their neighbors. Like the CIA deploying secret agents to turn an enemy, tumors use a similar strategy to manipulate nearby cells. The tumors’ agents are mitochondria, the ...

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells ...