The beating of a heart, the ability to learn and remember, and the movement of a sperm cell's tail all have at least one thing in common: They depend on the function of ion channels, the membrane ...

Cellular membranes are composed of lipid bilayers. The polar headgroups of lipids in the inner and outer leaflets are exposed to solutions, while the fatty acid tails of these lipids are in the ...

Osteoclasts are essential for bone resorption and interact with osteoblasts during bone remodeling. Ion channels and transporters located in the ruffled border or intracellular vesicles coordinate the ...

Microglia, the immune cells that protect the brain, are thought to maintain a healthy brain environment by removing unwanted substances through dynamic remodeling of the actin cytoskeleton, the cell's ...

Neuroinflammation is now recognized as a central driver instead of being merely a consequence of many neurological diseases, including neurodegenerative ...

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...

Researchers from Griffith University's National Center for Neuroimmunology and Emerging Diseases (NCNED) have made a discovery that could bring relief to those struggling with long COVID. In a ...

Maintenance of cardiac rhythm and pain sensation require the flow of ions across the membranes of all cells. Ion channels, which facilitate this movement, are protein assemblies that penetrate the ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies. Washbowls, bathtubs, and sinks are all fitted ...

(Nanowerk Spotlight) Biological brains compute using ions, not electrons. Every signal between neurons depends on charged atoms passing through protein channels embedded in cell membranes, a system ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited validation for hundreds of thousands of ...