Variant detection of multiple genes from a single tumor sample requires high-throughput molecular testing. To meet this demand, targeted next-generation sequencing (NGS) panels are useful in clinical ...

Janina Krumbeck, PhD, discusses the clinical advantages of next-generation sequencing over traditional culture and how this untargeted diagnostic approach provides comprehensive pathogen ...

The webinar series titled "The Basics of Next Generation Sequencing and its Application in Precision Oncology" aims to provide a comprehensive understanding of the fundamentals and practical ...

In the United States, healthcare professionals classify a disease as rare if it affects fewer than 200,000 individuals. As of August 7, 2024, the U.S. population consists of just under 336.9 million ...

For decades, formalin-fixing paraffin-embedding has been the preferred method for preserving biological samples for diagnostic research. Formalin is relatively inexpensive and can be used to preserve ...

As one of the early pioneers of next-gen sequencing (NGS) technology, Dr. Radoje (Rade) Drmanac is responsible for some of its most successful inventions. His storied career includes the development ...

As next-generation sequencing becomes more accessible, scientists gain unprecedented resolution to explore the underpinnings of health and disease. The information they have obtained has ...

This eBook explores next-generation sequencing (NGS) methods and their applications in neurological and cancer research, with key content from BioTechniques’ digital hub and Taylor & Francis journals, ...

Pattern of resistance on first-line EGFR-directed therapy in EGFR-positive metastatic non-small cell lung cancer. Utilizing TP53 mutation status and initial disease burden at presentation to ...