A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions. Molecular glues are emerging as powerful therapeutic ...

Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

Hydrogen/deuterium exchange coupled to mass spectrometry (HX-MS) is a valuable technique for analyzing the structural features and dynamic properties of individual proteins and large protein complexes ...

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed ...

This article explores how new technologies in plasma proteomics enable the simultaneous analysis of thousands of proteins, ...

A new laser technique decodes molecular vibrations to predict whether a drug will be effective, potentially cutting years ...

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune ...

Just how far mass spectrometry—the use of tools measuring the mass-to-charge ratio (m/z) of one or more molecules present in a sample—has progressed over the past century can be seen in a new exhibit ...

Hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) profiling tied a senescence gene region to chlorophyll ...